NR4A2 anticorps (AA 331-430)

N° du produit ABIN6944346

Détail du produit anti-NR4A2 anticorps

Antigène: NR4A2 (Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2))

Épitope: AA 331-430

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NR4A2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris, Rat

Homologie: Cow

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Nurr1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur NR4A2

Antigène: NR4A2 (Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2))

Autre désignation: Nurr1 (NR4A2 Produits)

Synonymes: anticorps nr41/42/43, anticorps Nr4a2, anticorps nurr1, anticorps not, anticorps rnr1, anticorps hzf-3, anticorps tinur, anticorps NGFI-B, anticorps HZF-3, anticorps NOT, anticorps NURR1, anticorps RNR1, anticorps TINUR, anticorps Nurr1, anticorps RNR-1, anticorps TINOR, anticorps ngf1b, anticorps nr4a2, anticorps zgc:92696, anticorps nuclear receptor subfamily 4 group A member 2, anticorps nuclear receptor, anticorps nuclear receptor subfamily 4, group A, member 2, anticorps nuclear receptor subfamily 4, group A, member 2b, anticorps NR4A2, anticorps nr41/42/43, anticorps nr4a2, anticorps Nr4a2, anticorps nr4a2b

Sujet:

Synonyms: Nur-ralated factor 1, Nuclear receptor-related factor 1, Orphan nuclear receptor NR4A2, Orphan nuclear receptor NURR1, Regenerating liver nuclear receptor 1, RNR-1, SL-322, Nuclear orphan receptor HZF-3, T-cell nuclear receptor NOT,HZF 3, HZF3, Immediate-early response protein NOT, Intermediate early receptor protein, NGFI B/nur77 beta type transcription factor homolog, NOT, NR4A2, NR4A2_HUMAN, Nuclear receptor subfamily 4 group A member 2, Nur related protein 1 homolog, Nurr 1,RNR 1, RNR1, TINUR, Transcriptionally inducible nuclear receptor, Transcriptionally inducible nuclear receptor related, Transcriptionally inducible nuclear receptor related 1, Transcriptionally-inducible nuclear receptor.

Background: Nuclear receptor and transcription factor, plays a role in development and maintenance of neurons synthesizing the neurotransmitter dopamine This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Four transcript variants encoding four distinct isoforms have been identified for this gene. Additional alternate splice variants may exist, but their full length nature has not been determined.

ID gène: 4929

UniProt: P43354

Pathways: Nuclear Receptor Transcription Pathway, Dopaminergic Neurogenesis, Steroid Hormone Mediated Signaling Pathway