ARPC5 anticorps

N° du produit ABIN6944379

Détail du produit anti-ARPC5 anticorps

Antigène: ARPC5 (Actin Related Protein 2/3 Complex, Subunit 5, 16kDa (ARPC5))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp ARPC5 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: Recombinant human p16 ARC around N-terminus

Clone: 8D8

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(ICC) 1:50-200
IHC()

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur ARPC5

Antigène: ARPC5 (Actin Related Protein 2/3 Complex, Subunit 5, 16kDa (ARPC5))

Autre désignation: p16 ARC (ARPC5 Produits)

Synonymes: anticorps arc16, anticorps p16-arc, anticorps ARPC5, anticorps APOBEC4, anticorps ARC16, anticorps dJ127C7.3, anticorps p16-Arc, anticorps MGC86407, anticorps 5830443F10Rik, anticorps arpc5, anticorps fb09c07, anticorps fb12b05, anticorps fc56c07, anticorps wu:fb09c07, anticorps wu:fb12b05, anticorps wu:fc56c07, anticorps actin related protein 2/3 complex subunit 5, anticorps actin related protein 2/3 complex subunit 5 L homeolog, anticorps actin related protein 2/3 complex, subunit 5, anticorps actin related protein 2/3 complex, subunit 5B, anticorps actin related protein 2/3 complex, subunit 5A, anticorps ARPC5, anticorps arpc5, anticorps arpc5.L, anticorps Arpc5, anticorps arpc5b, anticorps arpc5a

Sujet:

Synonyms: Actin-related protein 2/3 complex subunit 5, Arp2/3 complex 16 kDa subunit, p16-ARC, ARPC5

Background: Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9230079). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:29925947). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs).

ID gène: 10092

UniProt: O15511

Pathways: Signalisation RTK, Regulation of Actin Filament Polymerization