PLIN1 anticorps

N° du produit ABIN6944484

Détail du produit anti-PLIN1 anticorps

Antigène: PLIN1 (Perilipin 1 (PLIN1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp PLIN1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))

Réactivité croisée: Humain, Souris

Purification: Purified by Protein A.

Immunogène: Full length protein

Clone: 6C2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur PLIN1

Antigène: PLIN1 (Perilipin 1 (PLIN1))

Autre désignation: Perilipin A (PLIN1 Produits)

Synonymes: anticorps FPLD4, anticorps PERI, anticorps PLIN, anticorps PERIA, anticorps Plin, anticorps 6030432J05Rik, anticorps Peri, anticorps peri, anticorps plin, anticorps perilipin, anticorps LOC692833, anticorps perilipin 1, anticorps perilipin, anticorps perilipin 1 L homeolog, anticorps PLIN1, anticorps Plin1, anticorps plin1, anticorps LOC692833, anticorps plin1.L

Sujet:

Synonyms: Perilipin-1, Lipid droplet-associated protein, PLIN1

Background: Perilipins, members of the PAT protein family (named after lipid droplet proteins Perilipin, Adipophilin, and TIP47) are found exclusively at the surface of lipid droplets in adipocytes and steroidogenic cells. They have been suggested to function as regulators of lipolysis and triacylglycerol storage within adipose tissue. Four distinct isoforms ranging from perilipin A (57 kDa) to perilipin D (26 kDa) have been identified and they share an identical amino terminal sequences, and contain 26 consensus protein kinase A (PKA) phosphorylation sites. Perilipin C and D have been detected only in steroidogenic cells. Perilipin A is the most abundant form on the lipid droplets of adipocytes. The phosphorylation of perilipin by PKA, which is accompanied by the phosphorylation and translocation of hormone-sensitive lipase from the cytosol to the lipid droplets, promotes lipolysis. There is evidence for the presence of perilipin A in atheroma plaques suggesting that the protein may be involved in the development of therosclerosis by controlling as in adipocytes the hydrolysis of stored lipids.

ID gène: 5346

UniProt: O60240

Pathways: Lipid Metabolism