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SUN1 anticorps

SUN1 Reactivité: Humain, Rat WB, FACS, IF (cc), IF (p), IHC (p) Hôte: Lapin Monoclonal 2C4 unconjugated
N° du produit ABIN6945098
  • Antigène Voir toutes SUN1 Anticorps
    SUN1 (Sad1 and UNC84 Domain Containing 1 (SUN1))
    Reactivité
    • 18
    • 10
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Rat
    Hôte
    • 18
    • 4
    Lapin
    Clonalité
    • 11
    • 11
    Monoclonal
    Conjugué
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SUN1 est non-conjugé
    Application
    • 12
    • 8
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain, Rat
    Purification
    Purified by Protein A.
    Immunogène
    Recombinant protein corresponding to C-terminal human SUN1.
    Clone
    2C4
    Isotype
    IgG
    Top Product
    Discover our top product SUN1 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    SUN1 (Sad1 and UNC84 Domain Containing 1 (SUN1))
    Autre désignation
    SUN1 (SUN1 Produits)
    Synonymes
    anticorps UNC84A, anticorps 4632417G13Rik, anticorps 5730434D03Rik, anticorps Unc84a, anticorps mKIAA0810, anticorps Sun domain-containing protein 1, anticorps Sad1 and UNC84 domain containing 1, anticorps sun-1, anticorps SUN1, anticorps Sun1
    Sujet

    Synonyms: SUN domain-containing protein 1, Protein unc-84 homolog A, Sad1/unc-84 protein-like 1, SUN1, KIAA0810, UNC84A

    Background: As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Required for interkinetic nuclear migration (INM) and essential for nucleokinesis and centrosome-nucleus coupling during radial neuronal migration in the cerebral cortex and during glial migration. Involved in telomere attachment to nuclear envelope in the prophase of meiosis implicating a SUN1/2:KASH5 LINC complex in which SUN1 and SUN2 seem to act at least partial redundantly. Required for gametogenesis and involved in selective gene expression of coding and non-coding RNAs needed for gametogenesis. Helps to define the distribution of nuclear pore complexes (NPCs). Required for efficient localization of SYNE4 in the nuclear envelope. May be involved in nuclear remodeling during sperm head formation in spermatogenenis. May play a role in DNA repair by suppressing non-homologous end joining repair to facilitate the repair of DNA cross-links.

    ID gène
    23353
    UniProt
    O94901
    Pathways
    Maintenance of Protein Location
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