AATF anticorps (AA 1-39)

N° du produit ABIN6971349

Détail du produit anti-AATF anticorps

Antigène: AATF (Apoptosis Antagonizing Transcription Factor (AATF))

Épitope: AA 1-39

Reactivité: Humain, Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp AATF est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Attributs du produit: AATF/Che-1, or Apoptosis-antagonizing Transcription Factoris a key regulator of apoptosis through its interaction with MAP3K12 (DLK), as well as regulation of gene transcription and cell profileration through interaction with RNA polymerase II. AATF/Che-1 may promote cell proliferation by acting as a competitor of histone deacetylase 1 (HDAC1) interaction with the growth inhibiting protein pRb. AATF / Che-1 binding to pRb may displace HDAC1 from RB1/E2F complexes, leading to activation of E2F target genes and cell cycle progression. AATF / Che-1 antibody (mAb) (Clone 1B2D8) was raised in a Rat host. It has been validated for use in Immunofluorescence and Western blot, it has been shown to react with Human and Mouse samples.

Purification: Protein A Chromatography

Immunogène: This antibody was raised against peptide comprising amino acids 1-39 of mouse AATF (Apoptosis-antagonizing transcription factor) (NP_062790).

Clone: 1B2D8

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Détails sur AATF

Antigène: AATF (Apoptosis Antagonizing Transcription Factor (AATF))

Autre désignation: AATF / Che-1 (AATF Produits)

Synonymes: anticorps AATF, anticorps ded, anticorps che1, anticorps che-1, anticorps cb109, anticorps sb:cb109, anticorps wu:fc13d05, anticorps zgc:162071, anticorps CHE-1, anticorps CHE1, anticorps DED, anticorps 4933415H02Rik, anticorps 5830465M17Rik, anticorps Che-1, anticorps Trb, anticorps Ded, anticorps apoptosis antagonizing transcription factor, anticorps Apoptosis antagonizing transcription factor, anticorps apoptosis antagonizing transcription factor S homeolog, anticorps AATF, anticorps aatf, anticorps BFR2, anticorps NAEGRDRAFT_56916, anticorps Aatf, anticorps aatf.S

NCBI Accession: NP_062790

Pathways: Neurotrophin Signaling Pathway, SARS-CoV-2 Protein Interactome