VPS4B anticorps (AA 301-400)

N° du produit ABIN6989168

Détail du produit anti-VPS4B anticorps

Antigène: VPS4B (vps4b) (Vacuolar Protein Sorting 4 Homolog B (vps4b))

Épitope: AA 301-400

Reactivité: Humain, Souris, Poisson

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VPS4B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Réactivité croisée: Poisson, Humain, Souris

Homologie: Rat,Cow,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human VPS4B

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur VPS4B

Antigène: VPS4B (vps4b) (Vacuolar Protein Sorting 4 Homolog B (vps4b))

Autre désignation: VPS4B (vps4b Produits)

Synonymes: anticorps zgc:63682, anticorps vps4a, anticorps SKD1, anticorps SKD1B, anticorps VPS4-2, anticorps 8030489C12Rik, anticorps Skd1, anticorps vacuolar protein sorting 4 homolog B, anticorps vacuolar protein sorting 4 homolog B S homeolog, anticorps vacuolar protein sorting 4b homolog B (S. cerevisiae), anticorps vacuolar protein sorting 4 homolog B (S. cerevisiae), anticorps vacuolar protein sorting 4B, anticorps Vps4b, anticorps vps4b.S, anticorps vps4b, anticorps VPS4B

Sujet:

Synonyms: 8030489C12Rik, Cell migration inducing 1, Cell migration-inducing gene 1 protein, MGC116271, MIG1, Protein SKD1, Skd1, SKD1B, Suppressor of K(+) transport growth defect 1, Suppressor of K+ transport defect 1, Vacuolar protein sorting 4 homolog B (S. cerevisiae), Vacuolar protein sorting 4 homolog B, Vacuolar protein sorting 4b, Vacuolar protein sorting-associated protein 4B, Vacuolar protein sorting-associating protein 4B, VPS4 2, VPS42, Vps4b, VPS4B_HUMAN.

Background: Involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane fission. Redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. In conjunction with the ESCRT machinery also appears to function in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses).

ID gène: 9525

UniProt: O75351

Pathways: Dynamique des Microtubules, CXCR4-mediated Signaling Events