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LZTS2 anticorps (C-Term)

LZTS2 Reactivité: Humain ELISA, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6991079
  • Antigène Voir toutes LZTS2 Anticorps
    LZTS2 (Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2))
    Épitope
    • 10
    • 8
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 570-620, C-Term
    Reactivité
    • 25
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 23
    • 2
    Lapin
    Clonalité
    • 25
    Polyclonal
    Conjugué
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp LZTS2 est non-conjugé
    Application
    • 23
    • 14
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificité
    LZTS2 antibody is predicted to not cross-react with other LZTS family members.
    Purification
    LZTS2 Antibody is affinity chromatography purified via peptide column.
    Immunogène
    LZTS2 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human LZTS2. The immunogen is located within amino acids 570 - 620 of LZTS2.
    Isotype
    IgG
    Top Product
    Discover our top product LZTS2 Anticorps primaire
  • Indications d'application
    LZTS2 antibody can be used for detection of LZTS2 by immunohistochemistry at 5 μ,g/mL.

    Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    LZTS2 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,4 °C
    Stockage commentaire
    LZTS2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène
    LZTS2 (Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2))
    Autre désignation
    LZTS2 (LZTS2 Produits)
    Synonymes
    anticorps lapser1, anticorps MGC89253, anticorps si:dkey-250a11.1, anticorps LAPSER1, anticorps BC014695, anticorps mKIAA1813, anticorps Lapser1, anticorps leucine zipper, putative tumor suppressor 2, anticorps leucine zipper tumor suppressor 2, anticorps leucine zipper, putative tumor suppressor 2a, anticorps leucine zipper, putative tumor suppressor 2 S homeolog, anticorps lzts2, anticorps LZTS2, anticorps lzts2a, anticorps Lzts2, anticorps lzts2.S
    Sujet
    LZTS2 Antibody: The leucine zipper putative tumor suppressor 2 (LZTS2, also known as LAPSER1), a member of the LZTS family, is a negative regulator of the Wnt signaling pathway. It represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. LZTS2 is involved in cytokinesis and regulates katanin-mediated microtubule severing and release from the centrosome. LZTS2 may negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. LZTS2 is highly expressed in testis and prostate, but it is deleted in multiple cancers, including prostate tumors, suggesting that LZTS2 acts as a potential tumor suppressor.
    ID gène
    84445
    NCBI Accession
    NP_115805
    UniProt
    Q9BRK4
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