Angiotensin II Type 2 Receptor anticorps (AA 220-270)

N° du produit ABIN6991187

Détail du produit anti-Angiotensin II Type 2 Receptor anticorps

Antigène: Angiotensin II Type 2 Receptor (AGTR2) (Angiotensin II Receptor, Type 2 (AGTR2))

Épitope: AA 220-270

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Angiotensin II Type 2 Receptor est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Purification: AGTR2 Antibody is affinity chromatography purified via peptide column.

Immunogène: AGTR2 antibody was raised against a 16 amino acid synthetic peptide from near the center of human AGTR2. The immunogen is located within amino acids 220 - 270 of AGTR2.

Isotype: IgG

Information d'application

Indications d'application: AGTR2 antibody can be used for detection of AGTR2 by Western blot at 0.5 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunocytochemistry start at 5 μ,g/mL. For immunofluorescence start at 1 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in rat samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: AGTR2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: AGTR2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur Angiotensin II Type 2 Receptor

Antigène: Angiotensin II Type 2 Receptor (AGTR2) (Angiotensin II Receptor, Type 2 (AGTR2))

Autre désignation: AGTR2 (AGTR2 Produits)

Synonymes: anticorps AT2, anticorps ATGR2, anticorps MRX88, anticorps AI316812, anticorps AW107640, anticorps AT2-R, anticorps AT2R, anticorps AT₂R, anticorps at2, anticorps zgc:113016, anticorps AGTR2, anticorps angiotensin II receptor type 2, anticorps angiotensin II receptor, type 2, anticorps AGTR2, anticorps Agtr2, anticorps agtr2

Sujet: AGTR2 Antibody: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion that acts through at least two types of receptors, AGTR1 and AGTR2. It is an important effector controlling blood pressure and volume in the cardiovascular system and plays a major role in the development of the mammalian kidney and urinary tract. Like AGTR1, AGTR2 is a seven transmembrane G protein-coupled receptor (GPCR), but AGTR2 does not demonstrate most of the classic features of GPCR signaling. AGTR2 is involved in a wide range of activities, including the induction of neurite outgrowth and the inhibition of cellular proliferation, in addition to the known function of mediation of vasoconstriction.

Poids moléculaire: Predicted: 40 kDa

Observed: 36 kDa

ID gène: 186

UniProt: P50052

Pathways: ACE Inhibitor Pathway, Hormone Transport, Regulation of Systemic Arterial Blood Pressure by Hormones