APBA2 anticorps (AA 290-340)

N° du produit ABIN6991437

Détail du produit anti-APBA2 anticorps

Antigène: APBA2 (Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 (APBA2))

Épitope: AA 290-340

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APBA2 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Purification: APBA2 Antibody is affinity chromatography purified via peptide column.

Immunogène: APBA2 antibody was raised against an 18 amino acid synthetic peptide near the center of human APBA2. The immunogen is located within amino acids 290 - 340 of APBA2.

Isotype: IgG

Information d'application

Indications d'application: APBA2 antibody can be used for detection of APBA2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: APBA2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: APBA2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur APBA2

Antigène: APBA2 (Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 (APBA2))

Autre désignation: APBA2 (APBA2 Produits)

Synonymes: anticorps MGC83599, anticorps D15S1518E, anticorps HsT16821, anticorps LIN-10, anticorps MGC:14091, anticorps MINT2, anticorps X11-BETA, anticorps X11L, anticorps X11-like, anticorps XllL, anticorps mXllL, anticorps Mint2, anticorps amyloid beta precursor protein binding family A member 2, anticorps amyloid beta (A4) precursor protein-binding, family A, member 2 L homeolog, anticorps amyloid beta (A4) precursor protein-binding, family A, member 2, anticorps APBA2, anticorps apba2.L, anticorps Apba2

Sujet: APBA2 Antibody: APBA2, a member of the X11 protein family, is a phosphotyrosine-binding domain protein and is a neuronal adapter protein that interacts with amyloid precursor protein (APP) and neuritic plaques in the brains of patients with Alzheimer's disease. It stabilizes APP and inhibits production of proteolytic APP fragments including the Abeta peptide that is deposited in the brains of Alzheimer's disease patients. APBA2 is believed to be involved in signal transduction processes and is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Recent reports suggest that it may also be a candidate gene for autism.

ID gène: 321

NCBI Accession: NP_005494

UniProt: Q99767

Pathways: Synaptic Vesicle Exocytosis