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SLC39A1 anticorps (N-Term)

SLC39A1 Reactivité: Humain, Souris ELISA, WB, IF, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6991451
  • Antigène Voir toutes SLC39A1 Anticorps
    SLC39A1 (Solute Carrier Family 39 (Zinc Transporter), Member 1 (SLC39A1))
    Épitope
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 40-90, N-Term
    Reactivité
    • 22
    • 11
    • 9
    • 4
    Humain, Souris
    Hôte
    • 27
    Lapin
    Clonalité
    • 27
    Polyclonal
    Conjugué
    • 10
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SLC39A1 est non-conjugé
    Application
    • 15
    • 8
    • 3
    • 3
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificité
    At least two isoforms of ZIP1 are known to exist, this antibody will detect both isoforms. ZIP1 antibody is predicted not to cross-react with other ZIP family proteins.
    Purification
    ZIP1 Antibody is affinity chromatography purified via peptide column.
    Immunogène
    ZIP1 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human ZIP1. The immunogen is located within amino acids 40 - 90 of ZIP1.
    Isotype
    IgG
    Top Product
    Discover our top product SLC39A1 Anticorps primaire
  • Indications d'application
    ZIP1 antibody can be used for detection of ZIP1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    ZIP1 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,4 °C
    Stockage commentaire
    ZIP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène
    SLC39A1 (Solute Carrier Family 39 (Zinc Transporter), Member 1 (SLC39A1))
    Autre désignation
    ZIP1 (SLC39A1 Produits)
    Synonymes
    anticorps cb629, anticorps DrZIP1, anticorps sb:cb629, anticorps zgc:111852, anticorps frzip1p, anticorps zip1, anticorps zirtl, anticorps ZIP1, anticorps ZIRTL, anticorps Zip1, anticorps Zirtl, anticorps solute carrier family 39 (zinc transporter), member 1, anticorps solute carrier family 39 member 1, anticorps solute carrier family 39 member 1 L homeolog, anticorps slc39a1, anticorps Slc39a1, anticorps SLC39A1, anticorps slc39a1.L
    Sujet
    ZIP1 Antibody: ZIP1, also known as ZIRTL (zinc-iron regulated transporter-like), is the first mammalian member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP1 expression is markedly downregulated in a number of cancerous tissues and is thought to function as a tumor suppressor gene in prostate cancer. More recent studies have shown that overexpression of ZIP1 and concomitant increased levels of intracellular zinc in PC-3 cells cause a significant inhibition of NF-κ,B, leading to down-regulation of the antiapoptotic protein Bcl-2, Bcl-XL, and the apoptosis inhibitor XIAP, reducing the malignant potential of prostate cancer cells in vitro and in vivo.
    Poids moléculaire
    Predicted: 13, 36 kDa

    Observed: 38 kDa
    ID gène
    27173
    NCBI Accession
    NP_055252
    UniProt
    Q9NY26
    Pathways
    Autophagy
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