LMX1B anticorps (C-Term)

N° du produit ABIN6991776

Détail du produit anti-LMX1B anticorps

Antigène: LMX1B (LIM Homeobox Transcription Factor 1, beta (LMX1B))

Épitope: AA 280-330, C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LMX1B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificité: At least three isoforms are known to exist. This antibody is predicted to not cross-react with LMX1A.

Purification: LMX1B Antibody is affinity chromatography purified via peptide column.

Immunogène: Rabbit polyclonal LMX1B antibody was raised against a 17 amino acid peptide near the carboxy terminus of human LMX1B. The immunogen is located within amino acids 280 - 330 of LMX1B.

Isotype: IgG

Information d'application

Indications d'application: LMX1B antibody can be used for detection of LMX1B by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human and mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: LMX1B Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: LMX1B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur LMX1B

Antigène: LMX1B (LIM Homeobox Transcription Factor 1, beta (LMX1B))

Autre désignation: LMX1B (LMX1B Produits)

Synonymes: anticorps LMX1.2, anticorps NPS1, anticorps LMX, anticorps LMX1, anticorps LMX1.1, anticorps lmx1b, anticorps lmx1b.1, anticorps Xlmx1b, anticorps lmx1b.2, anticorps LIM homeobox transcription factor 1 beta, anticorps LIM homeobox transcription factor 1, beta b, anticorps LIM homeobox transcription factor 1, beta, gene 1 S homeolog, anticorps LIM homeobox transcription factor 1, beta a, anticorps LMX1B, anticorps Lmx1b, anticorps lmx1bb, anticorps lmx1b.1.S, anticorps lmx1ba

Sujet: LMX1B Antibody: The LIM homeobox transcription factor 1B (LMX1B) belongs to the LIM-homeodomain family. Members of this family are known to be important for pattern formation during development. LMX1B regulates mid-hindbrain patterning, LMX1B-null mice embryos have a severe reduction in the number of midbrain dopaminergic neurons compared to wild-type. While LMX1B appears to be important for both the development and the survival of dopamine neurons, the related LMX1A is crucial for the differentiation of these cells. However, LMX1A and LMX1B function cooperatively to regulated the proliferation, specification and differentiation of midbrain dopaminergic neuronal progenitors.

Poids moléculaire: 45 kDa

ID gène: 4010

NCBI Accession: NP_001167617

UniProt: O60663

Pathways: Dopaminergic Neurogenesis