LIN54 anticorps (C-Term)

N° du produit ABIN6992048

Détail du produit anti-LIN54 anticorps

Antigène: LIN54 (Lin-54 Homolog (LIN54))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LIN54 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificité: LIN54 antibody is human, mouse, and rat reactive. Multiple isoforms of LIN54 are known to exist.

Purification: LIN54 antibody is affinity chromatography purified via peptide column.

Immunogène: LIN54 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human LIN54. The immunogen is located within the last 50 amino acids of LIN54.

Isotype: IgG

Information d'application

Indications d'application: LIN54 antibody can be used for detection of LIN54 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: LIN54 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: LIN54 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur LIN54

Antigène: LIN54 (Lin-54 Homolog (LIN54))

Autre désignation: LIN54 (LIN54 Produits)

Synonymes: anticorps CXCDC1, anticorps JC8.6, anticorps MIP120, anticorps 4832414L08, anticorps AI461788, anticorps mKIAA2037, anticorps RGD1311361, anticorps lin-54 DREAM MuvB core complex component, anticorps lin-54 homolog (C. elegans), anticorps LIN54, anticorps Lin54

Sujet: LIN54 is a component of the LIN, or DREAM, complex, an essential regulator of cell cycle genes. This complex functions as a transcriptional repressor by binding to promoters of E2F target genes that regulate the G1/S transition (1). LIN54 is required for cell cycle progression and can bind to the cdc2 promoter in a sequence-specific manner (2).

Poids moléculaire: Predicted: 88 kDa

Observed: 82 kDa

ID gène: 132660

NCBI Accession: NP_919258

UniProt: Q6MZP7

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases