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SLC30A8 anticorps (N-Term)

SLC30A8 Reactivité: Humain WB, ELISA, IHC (p), IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6992184
  • Antigène Voir toutes SLC30A8 Anticorps
    SLC30A8 (Solute Carrier Family 30 (Zinc Transporter), Member 8 (SLC30A8))
    Épitope
    • 13
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 42
    • 23
    • 23
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 44
    • 1
    Lapin
    Clonalité
    • 45
    Polyclonal
    Conjugué
    • 14
    • 7
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SLC30A8 est non-conjugé
    Application
    • 37
    • 16
    • 10
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Specificité
    Two isoforms of SLC30A8 are known to exist, this antibody will detect both isoforms. This SLC30A8 antibody is predicted to not cross-react with other members of the SLC30 protein family.
    Purification
    SLC30A8 Antibody is affinity chromatography purified via peptide column.
    Immunogène
    SLC30A8 antibody was raised against a peptide corresponding to 14 amino acids near the amino terminus of human SLC30A8.
    Isotype
    IgG
    Top Product
    Discover our top product SLC30A8 Anticorps primaire
  • Indications d'application
    SLC30A8 antibody can be used for Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    SLC30A8 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,4 °C
    Stockage commentaire
    SLC30A8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène
    SLC30A8 (Solute Carrier Family 30 (Zinc Transporter), Member 8 (SLC30A8))
    Autre désignation
    SLC30A8 (SLC30A8 Produits)
    Synonymes
    anticorps C820002P14Rik, anticorps ZnT-8, anticorps ZnT8, anticorps slc30a3, anticorps znt8, anticorps ZNT8, anticorps E130106K10Rik, anticorps Gm212, anticorps wu:fe49g03, anticorps RGD1305098, anticorps solute carrier family 30 member 8, anticorps solute carrier family 30 (zinc transporter), member 8, anticorps solute carrier family 30 (zinc transporter), member 8 L homeolog, anticorps solute carrier family 30, member 10, anticorps SLC30A8, anticorps Slc30a8, anticorps slc30a8.L, anticorps slc30a8, anticorps Slc30a10
    Sujet
    SLC30A8 Antibody: SLC30A8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles and is expressed at a high level in the pancreas, particularly in islets of Langerhans, and co-localizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells (1). Allelic variants of SLC30A8 have been identified as major genetic risk factors for the development of Type 2 diabetes (2), but no genetic association has been found with Type 1 diabetes (3). SLC30A8 expression in ?-cells was found to be influenced by cytokine expression, particularly IFN-gamma and IL-1beta (4).
    Poids moléculaire
    Predicted: 35, 41 kDa

    Observed: 35, 41 kDa
    ID gène
    169026
    NCBI Accession
    NP_776250
    UniProt
    Q8IWU4
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Carbohydrate Homeostasis, Transition Metal Ion Homeostasis
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