KNSTRN anticorps

N° du produit ABIN7233849

Détail du produit anti-KNSTRN anticorps

Antigène: KNSTRN (Kinetochore-Localized Astrin/SPAG5 Binding Protein (KNSTRN))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KNSTRN est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant Human Small kinetochore-associated protein protein

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2 mg/mL

Buffer: PBS with 0.05 % Proclin300 and 50 % glycerol, pH 7.4.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur KNSTRN

Antigène: KNSTRN (Kinetochore-Localized Astrin/SPAG5 Binding Protein (KNSTRN))

Autre désignation: C15orf23 (KNSTRN Produits)

Synonymes: anticorps 1700025D04Rik, anticorps C15orf23, anticorps D2Ertd750e, anticorps SKAP, anticorps Traf4af1, anticorps TRAF4AF1, anticorps kinetochore-localized astrin/SPAG5 binding, anticorps kinetochore localized astrin/SPAG5 binding protein, anticorps kinetochore-localized astrin/SPAG5 binding protein, anticorps Knstrn, anticorps KNSTRN

Sujet: Essential component of the mitotic spindle required for faithful chromosome segregation and progression into anaphase . Promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments. Required for kinetochore oscillations and dynamics of microtubule plus-ends during live cell mitosis, possibly by forming a link between spindle microtubule plus-ends and mitotic chromosomes to achieve faithful cell division.

Poids moléculaire:

Observed_MW: 35 kDa

Calculated_MW: 35 kDa

UniProt: Q9Y448

Pathways: M Phase