ADAM10 anticorps

N° du produit ABIN7240415

Détail du produit anti-ADAM10 anticorps

Antigène: ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADAM10 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant protein of human ADAM10

Isotype: IgG

Information d'application

Indications d'application: WB 1:200-1:1000, IHC 1:25-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ADAM10

Antigène: ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))

Autre désignation: CD156c (ADAM10 Produits)

Synonymes: anticorps ADAM10, anticorps Adam10, anticorps adam10, anticorps wu:fc03d12, anticorps ad10, anticorps cd156c, anticorps kuz, anticorps kuzbanian, anticorps madm, anticorps xadam10, anticorps ADAM-10, anticorps ADAM 10, anticorps AD10, anticorps CD156c, anticorps HsT18717, anticorps MADM, anticorps 1700031C13Rik, anticorps LOC100219653, anticorps zgc:64203, anticorps ADAM metallopeptidase domain 10, anticorps ADAM metallopeptidase domain 10a, anticorps ADAM metallopeptidase domain 10 S homeolog, anticorps a disintegrin and metallopeptidase domain 10, anticorps ADAM metallopeptidase domain 10b, anticorps ADAM10, anticorps Adam10, anticorps adam10a, anticorps adam10.S, anticorps adam10b

Sujet: Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Cleaves the membrane-bound precursor of TNF-alpha at '76-Ala-|-Val-77' to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including heparin-binding epidermal growth-like factor, ephrin-A2 and for constitutive and regulated alpha-secretase cleavage of amyloid precursor protein (APP).

Poids moléculaire: 84 kDa

UniProt: O14672

Pathways: Signalisation Notch, EGFR Signaling Pathway