DCC anticorps
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- Antigène Voir toutes DCC Anticorps
- DCC (Deleted in Colorectal Carcinoma (DCC))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DCC est non-conjugé
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Application
- ELISA, Immunohistochemistry (IHC)
- Attributs du produit
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogène
- Synthetic peptide of human DCC
- Isotype
- IgG
- Top Product
- Discover our top product DCC Anticorps primaire
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- Indications d'application
- IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.7 mg/mL
- Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- DCC (Deleted in Colorectal Carcinoma (DCC))
- Autre désignation
- DCC (DCC Produits)
- Synonymes
- anticorps CRC18, anticorps CRCR1, anticorps IGDCC1, anticorps MRMV1, anticorps DCC, anticorps zdcc, anticorps C030036D22Rik, anticorps Igdcc1, anticorps xdcc, anticorps XDCCa, anticorps dcca-A, anticorps Dcc, anticorps DCC netrin 1 receptor, anticorps deleted in colorectal carcinoma, anticorps netrin receptor DCC, anticorps DCC, anticorps dcc, anticorps Dcc, anticorps LOC100712666
- Sujet
- This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma.
- NCBI Accession
- NP_005206
- UniProt
- P43146
- Pathways
- Regulation of Cell Size
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