CKMT1 anticorps

N° du produit ABIN7247918

Détail du produit anti-CKMT1 anticorps

Antigène: CKMT1 (Creatine Kinase, Mitochondrial 1, Ubiquitous (CKMT1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CKMT1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of human CKMT1A/CKMT1B

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.68 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CKMT1

Antigène: CKMT1 (Creatine Kinase, Mitochondrial 1, Ubiquitous (CKMT1))

Autre désignation: CKMT1A/CKMT1B (CKMT1 Produits)

Sujet: Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80 % homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 47 kDa

UniProt: P12532