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NR3C2 anticorps

NR3C2 Reactivité: Humain, Rat, Souris IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7249812
  • Antigène Voir toutes NR3C2 Anticorps
    NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
    Reactivité
    • 57
    • 45
    • 29
    • 17
    • 7
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Humain, Rat, Souris
    Hôte
    • 70
    • 5
    Lapin
    Clonalité
    • 69
    • 6
    Polyclonal
    Conjugué
    • 27
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Cet anticorp NR3C2 est non-conjugé
    Application
    • 73
    • 39
    • 39
    • 20
    • 14
    • 12
    • 10
    • 8
    • 3
    • 3
    • 2
    • 1
    Immunohistochemistry (IHC)
    Attributs du produit
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogène
    KLH conjugated Synthetic peptide corresponding to Mouse Mineralocorticoid receptor
    Isotype
    IgG
    Top Product
    Discover our top product NR3C2 Anticorps primaire
  • Indications d'application
    IHC 1:200-1:800
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.3 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
    Autre désignation
    Mineralocorticoid receptor (NR3C2 Produits)
    Synonymes
    anticorps mr, anticorps si:ch211-189l17.1, anticorps LOC100302443, anticorps NR3C2, anticorps LOC443144, anticorps MLR, anticorps MR, anticorps MCR, anticorps NR3C2VIT, anticorps Mlr, anticorps mlr, anticorps nuclear receptor subfamily 3, group C, member 2, anticorps nuclear receptor subfamily 3 group C member 2, anticorps mineralocorticoid receptor, anticorps nuclear receptor subfamily 3 group C member 2 L homeolog, anticorps nr3c2, anticorps NR3C2, anticorps LOC443144, anticorps Nr3c2, anticorps nr3c2.L
    Sujet
    This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants.
    UniProt
    P08235, Q8VII8, P22199
    Pathways
    ACE Inhibitor Pathway, Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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