Iba1 anticorps

N° du produit ABIN7249968

Détail du produit anti-Iba1 anticorps

Antigène: Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

Reactivité: Rat, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Iba1 est non-conjugé

Application: Immunohistochemistry (IHC)

Attributs du produit: Monoclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse IBA-1

Clone: 5G4E7

Isotype: IgG

Information d'application

Indications d'application: IHC 1:200-1:800

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.4 mg/mL

Buffer: PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Iba1

Antigène: Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

Autre désignation: AIF1 (IBA1 Produits)

Synonymes: anticorps AIF-1, anticorps IBA1, anticorps IRT-1, anticorps IRT1, anticorps AI607846, anticorps D17H6S50E, anticorps G1, anticorps Iba1, anticorps Bart1, anticorps iba1, anticorps mrf-1, anticorps fa04b11, anticorps wu:fa04b11, anticorps AIF, anticorps AIF1, anticorps aif1, anticorps allograft inflammatory factor 1, anticorps AIF1, anticorps Aif1, anticorps aif1

Sujet: This gene is induced by cytokines and interferon. Its protein product is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma. Three transcript variants encoding different isoforms have been found for this gene.Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.

UniProt: O70200

Pathways: Smooth Muscle Cell Migration