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COL1A1 anticorps

COL1A1 Reactivité: Humain, Rat, Souris IHC (p) Hôte: Souris Monoclonal 3C3 unconjugated
N° du produit ABIN7250383
  • Antigène Voir toutes COL1A1 Anticorps
    COL1A1 (Collagen, Type I, alpha 1 (COL1A1))
    Reactivité
    • 57
    • 29
    • 24
    • 12
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Rat, Souris
    Hôte
    • 67
    • 11
    Souris
    Clonalité
    • 58
    • 20
    Monoclonal
    Conjugué
    • 41
    • 9
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp COL1A1 est non-conjugé
    Application
    • 52
    • 36
    • 34
    • 11
    • 9
    • 9
    • 7
    • 4
    • 3
    • 2
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Attributs du produit
    Monoclonal Antibody
    Purification
    Protein A purification
    Immunogène
    Synthetic Peptide of Collagen I
    Clone
    3C3
    Isotype
    IgG
    Top Product
    Discover our top product COL1A1 Anticorps primaire
  • Indications d'application
    IHC 1:50-300
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    COL1A1 (Collagen, Type I, alpha 1 (COL1A1))
    Autre désignation
    COL1A1 (COL1A1 Produits)
    Synonymes
    anticorps OI4, anticorps Col1a-1, anticorps Cola-1, anticorps Cola1, anticorps Mov-13, anticorps Mov13, anticorps COLIA1, anticorps col1a1, anticorps MGC52532, anticorps COL1A1, anticorps COL1A2, anticorps alpha1(I), anticorps cb21, anticorps sb:cb21, anticorps sb:cb384, anticorps wu:fa99c12, anticorps wu:fb02c06, anticorps alpha3(I), anticorps col1a3, anticorps hm:zeh0348, anticorps wu:fa95h05, anticorps wu:fd02a10, anticorps wu:fj59a10, anticorps collagen type I alpha 1 chain, anticorps collagen, type I, alpha 1, anticorps collagen, type I, alpha 1 S homeolog, anticorps collagen alpha-1(I) chain, anticorps collagen type I alpha 2 chain, anticorps collagen, type I, alpha 1a, anticorps collagen 1a1, anticorps collagen, type I, alpha 1b, anticorps COL1A1, anticorps Col1a1, anticorps col1a1.S, anticorps LOC397571, anticorps COL1A2, anticorps col1a1a, anticorps col1a1, anticorps col1a1b
    Sujet
    COL1A1 (Collagen Type I Alpha 1 Chain) is a Protein Coding gene. Diseases associated with COL1A1 include Caffey Disease and Osteogenesis Imperfecta, Type I. Among its related pathways are Collagen chain trimerization and Transcription_Role of VDR in regulation of genes involved in osteoporosis. GO annotations related to this gene include identical protein binding and platelet-derived growth factor binding. An important paralog of this gene is COL2A1.This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.
    UniProt
    P02452
    Pathways
    Sensory Perception of Sound, Autophagy, Growth Factor Binding
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