FNDC3B anticorps

N° du produit ABIN7252033

Détail du produit anti-FNDC3B anticorps

Antigène: FNDC3B (Fibronectin Type III Domain Containing 3B (FNDC3B))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FNDC3B est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Full length fusion protein

Isotype: IgG

Information d'application

Indications d'application: IHC 1:30-1:150, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.8 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur FNDC3B

Antigène: FNDC3B (Fibronectin Type III Domain Containing 3B (FNDC3B))

Autre désignation: FNDC3B (FNDC3B Produits)

Synonymes: anticorps FAD104, anticorps PRO4979, anticorps YVTM2421, anticorps 1600019O04Rik, anticorps AW550168, anticorps Fad104, anticorps mKIAA4164, anticorps RGD1311673, anticorps FNDC3B, anticorps DKFZp469D136, anticorps fibronectin type III domain containing 3B, anticorps FNDC3B, anticorps Fndc3b, anticorps fndc3b

Sujet: Adipogenesis, the process of transforming pre-adipocytes into mature fat cells, is of particular interest due to the role adipocytes play in obesity and type II diabetes. Adipocytes have been shown to affect a variety of functions, including hemostasis, angiogenesis and energy balance, by secreting hormones and bioactive peptides. The FNDC3B protein, also designated FAD104 (factor for adipocyte differentiation 104) or HCV NS5A-binding protein 37, is expressed during early adipogenesis. Belonging to the FNDC3 family of proteins, FNDC3B is a 1,204 amino acid protein that contains nine fibronectin type-III domains. FNDC3B-deficient mice die within one day of birth, suggesting that FNDC3B is crucial for postpartum survival. Mouse embryonic fibroblasts (MEFs) with loss of FNDC3B function displayed a reduction in stress fiber formation, indicating a role for FNDC3B in cell proliferation, adhesion, spreading and migration.

UniProt: Q53EP0

Pathways: Positive Regulation of fat Cell Differentiation