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PYCARD anticorps

PYCARD Reactivité: Humain, Souris, Rat IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7255624
  • Antigène Voir toutes PYCARD Anticorps
    PYCARD (PYD and CARD Domain Containing (PYCARD))
    Reactivité
    • 57
    • 9
    • 8
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 48
    • 7
    • 3
    Lapin
    Clonalité
    • 46
    • 12
    Polyclonal
    Conjugué
    • 33
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp PYCARD est non-conjugé
    Application
    • 41
    • 23
    • 14
    • 13
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Attributs du produit
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein of human ASC / TMS1 (NP_037390.2).
    Isotype
    IgG
    Top Product
    Discover our top product PYCARD Anticorps primaire
  • Indications d'application
    IHC 1:50-1:200 IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    PYCARD (PYD and CARD Domain Containing (PYCARD))
    Autre désignation
    ASC / TMS1 (PYCARD Produits)
    Synonymes
    anticorps ASC, anticorps CARD5, anticorps TMS, anticorps TMS-1, anticorps TMS1, anticorps 9130417A21Rik, anticorps Asc, anticorps TNS1, anticorps masc, anticorps asc1, anticorps zAsc, anticorps zgc:109874, anticorps PYD and CARD domain containing, anticorps PYCARD, anticorps Pycard, anticorps pycard
    Sujet
    This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm, however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene.
    ID gène
    29108
    UniProt
    Q9ULZ3
    Pathways
    Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation, Inflammasome
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