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ZNF828 anticorps

ZNF828 Reactivité: Humain, Souris IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7255730
  • Antigène Voir toutes ZNF828 Anticorps
    ZNF828 (Zinc Finger Protein 828 (ZNF828))
    Reactivité
    • 37
    • 21
    • 16
    • 3
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 35
    • 2
    Lapin
    Clonalité
    • 37
    Polyclonal
    Conjugué
    • 13
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ZNF828 est non-conjugé
    Application
    • 36
    • 13
    • 13
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Immunofluorescence (IF)
    Attributs du produit
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein of human CHAMP1 (NP_115812.1).
    Isotype
    IgG
    Top Product
    Discover our top product ZNF828 Anticorps primaire
  • Indications d'application
    IF 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    ZNF828 (Zinc Finger Protein 828 (ZNF828))
    Autre désignation
    CHAMP1 (ZNF828 Produits)
    Synonymes
    anticorps ZNF828, anticorps C13orf8, anticorps CAMP, anticorps CHAMP, anticorps AA675043, anticorps AI116001, anticorps D8Ertd457e, anticorps D8Ertd569e, anticorps Zfp828, anticorps Znf828, anticorps mKIAA1802, anticorps chromosome alignment maintaining phosphoprotein 1, anticorps CHAMP1, anticorps Champ1
    Sujet
    CHAMP1 (chromosome alignment maintaining phosphoprotein 1), also known as ZNF828 or C13orf8, is a 812 amino acid protein containing one C2H2-type zinc finger. CHAMP1 is required for the proper alignment of chromosomes during metaphase, undergoing CDK1-dependent phosphorylation at multiple sites during mitosis. The phosphorylation counteracts the negative chromosomal alignment regulation of the zinc-finger domain of CHAMP1. One region of CHAMP1, the FPE region, is responsible for spindle and kinetochore localization, which is essential for proper chromosome alignment. CHAMP1 interacts with MAD2L2, PGOZ, CBX1, CBX3 and CBX5, and may recruit CENPE and CENPF to the kinetochore. The CHAMP1 gene is located on chromosome 13 and is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat and chicken.
    ID gène
    283489
    UniProt
    Q96JM3
    Pathways
    Maintenance of Protein Location
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