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SMAD7 anticorps

SMAD7 Reactivité: Humain, Souris, Rat WB, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7256046
  • Antigène Voir toutes SMAD7 Anticorps
    SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))
    Reactivité
    • 44
    • 25
    • 23
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 37
    • 7
    Lapin
    Clonalité
    • 38
    • 6
    Polyclonal
    Conjugué
    • 27
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SMAD7 est non-conjugé
    Application
    • 24
    • 17
    • 14
    • 14
    • 9
    • 8
    • 8
    • 4
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Attributs du produit
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogène
    A synthetic peptide of human SMAD7 (NP_005895.1).
    Isotype
    IgG
    Top Product
    Discover our top product SMAD7 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000 IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))
    Autre désignation
    SMAD7 (SMAD7 Produits)
    Synonymes
    anticorps CRCS3, anticorps MADH7, anticorps MADH8, anticorps Smad7a, anticorps Madh7, anticorps Smad10, anticorps madh7, anticorps xsmad7, anticorps wu:fj60c10, anticorps SMAD family member 7, anticorps SMAD family member 7 L homeolog, anticorps SMAD7, anticorps Smad7, anticorps smad7.L, anticorps smad7
    Sujet
    The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene.
    Poids moléculaire

    Observed_MW: 46 kDa

    Calculated_MW: 23 kDa/46 kDa

    ID gène
    4092
    UniProt
    O15105
    Pathways
    Interferon-gamma Pathway, Cell-Cell Junction Organization
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