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HLA-DPB1 anticorps

HLA-DPB1 Reactivité: Humain, Souris, Rat IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7256818
  • Antigène Voir toutes HLA-DPB1 Anticorps
    HLA-DPB1 (Major Histocompatibility Complex, Class II, DP beta 1 (HLA-DPB1))
    Reactivité
    • 63
    • 20
    • 2
    • 2
    • 2
    Humain, Souris, Rat
    Hôte
    • 50
    • 13
    Lapin
    Clonalité
    • 45
    • 18
    Polyclonal
    Conjugué
    • 34
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HLA-DPB1 est non-conjugé
    Application
    • 49
    • 28
    • 27
    • 21
    • 16
    • 13
    • 13
    • 11
    • 4
    • 4
    • 3
    • 2
    Immunohistochemistry (IHC)
    Attributs du produit
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein of human HLA-DPB1 (NP_002112.3).
    Isotype
    IgG
    Top Product
    Discover our top product HLA-DPB1 Anticorps primaire
  • Indications d'application
    IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    HLA-DPB1 (Major Histocompatibility Complex, Class II, DP beta 1 (HLA-DPB1))
    Autre désignation
    HLA-DPB1 (HLA-DPB1 Produits)
    Synonymes
    anticorps PATR-DPB1, anticorps B-LB, anticorps B-LB2, anticorps B-LB21, anticorps BLB1, anticorps GSP-BLB1, anticorps DPB1, anticorps HLA-DP, anticorps HLA-DP1B, anticorps HLA-DPB, anticorps major histocompatibility complex, class II, DP beta 1, anticorps Major histocompatibility complex class II beta chain BLB1, anticorps PATR-DPB1, anticorps BLB1, anticorps HLA-DPB1
    Sujet
    HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.
    ID gène
    3115
    UniProt
    P04440
    Pathways
    TCR Signaling, Cancer Immune Checkpoints
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