MOCOS anticorps

N° du produit ABIN7257806

Détail du produit anti-MOCOS anticorps

Antigène: MOCOS (Molybdenum Cofactor Sulfurase (MOCOS))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MOCOS est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human MOCOS (NP_060417.2).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MOCOS

Antigène: MOCOS (Molybdenum Cofactor Sulfurase (MOCOS))

Autre désignation: MOCOS (MOCOS Produits)

Synonymes: anticorps HMCS, anticorps MCS, anticorps MOS, anticorps 1110018O12Rik, anticorps DDBDRAFT_0217046, anticorps DDBDRAFT_0252757, anticorps DDB_0217046, anticorps DDB_0252757, anticorps Og, anticorps im:7142948, anticorps mocos, anticorps molybdenum cofactor sulfurase, anticorps MOCOS, anticorps Mocos, anticorps AOR_1_1090144, anticorps mocos, anticorps MCYG_05594, anticorps VDBG_04857, anticorps MGYG_02684, anticorps TERG_06775, anticorps mal

Sujet: This gene encodes an enzyme that sulfurates the molybdenum cofactor which is required for activation of the xanthine dehydrogenase (XDH) and aldehyde oxidase (AO) enzymes. XDH catalyzes the conversion of hypoxanthine to uric acid via xanthine, as well as the conversion of allopurinol to oxypurinol, and pyrazinamide to 5-hydroxy pyrazinamide. Mutations in this gene cause the metabolic disorder classical xanthinuria type II which is characterized by the loss of XDH/XO and AO enzyme activity, decreased levels of uric acid in the urine, increased levels of xanthine and hypoxanthine in the serum and urine, formation of xanthine stones in the urinary tract, and myositis due to tissue deposition of xanthine.

Poids moléculaire:

Observed_MW: 98 kDa

Calculated_MW: 98 kDa

ID gène: 55034

UniProt: Q96EN8

Pathways: Response to Water Deprivation, ER-Nucleus Signaling