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GRK2 anticorps

KO Validated ADRBK1 Reactivité: Humain, Souris, Rat WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7259288
  • Antigène Voir toutes GRK2 (ADRBK1) Anticorps
    GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
    Reactivité
    • 98
    • 77
    • 56
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    Humain, Souris, Rat
    Hôte
    • 92
    • 8
    • 2
    • 2
    Lapin
    Clonalité
    • 87
    • 17
    Polyclonal
    Conjugué
    • 58
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GRK2 est non-conjugé
    Application
    • 56
    • 45
    • 30
    • 17
    • 14
    • 13
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificité
    This antibody ist KO validated.
    Attributs du produit
    Polyclonal Antibody
    Purification
    Affinity purification
    Classe de qualité
    KO Validated
    Immunogène
    Recombinant fusion protein of human ADRBK1 (NP_001610.2).
    Isotype
    IgG
    Top Product
    Discover our top product ADRBK1 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000 IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
    Autre désignation
    ADRBK1 (ADRBK1 Produits)
    Synonymes
    anticorps Adrbk-1, anticorps Bark-1, anticorps GRK2, anticorps betaARK1, anticorps BARK1, anticorps BETA-ARK1, anticorps GRK-2, anticorps Grk2, anticorps beta-adrenergic receptor kinase 1, anticorps G protein-coupled receptor kinase 2, anticorps Tsp_00497, anticorps grk2, anticorps Grk2, anticorps GRK2
    Sujet
    The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.
    Poids moléculaire

    Observed_MW: 80 kDa

    Calculated_MW: 79 kDa

    ID gène
    156
    UniProt
    P25098
    Pathways
    EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling
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