PSMC2 anticorps

N° du produit ABIN7260033

Détail du produit anti-PSMC2 anticorps

Antigène: PSMC2 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 2 (PSMC2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMC2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human PSMC2 (NP_002794.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PSMC2

Antigène: PSMC2 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 2 (PSMC2))

Autre désignation: PSMC2 (PSMC2 Produits)

Synonymes: anticorps xMSS1, anticorps psmc2, anticorps DDBDRAFT_0168337, anticorps DDBDRAFT_0232966, anticorps DDB_0168337, anticorps DDB_0232966, anticorps MSS1, anticorps Nbla10058, anticorps S7, anticorps NCU02840.1, anticorps zgc:63995, anticorps proteasome 26S subunit, ATPase 2 L homeolog, anticorps proteasome (prosome, macropain) 26S subunit, ATPase 2, anticorps 26S protease regulatory subunit 7, anticorps proteasome 26S subunit, ATPase 2, anticorps regulatory particle, ATPase-like-1, anticorps psmc2.L, anticorps psmc2, anticorps psmC2, anticorps PSMC2, anticorps rpt-1, anticorps GL50803_21331, anticorps EHI_080890, anticorps UREG_01412, anticorps PITG_10169, anticorps Psmc2, anticorps GL50803_86683, anticorps Tsp_09237

Sujet: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit has been shown to interact with several of the basal transcription factors so, in addition to participation in proteasome functions, this subunit may participate in the regulation of transcription. This subunit may also compete with PSMC3 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Poids moléculaire:

Observed_MW: 49 kDa

Calculated_MW: 33 kDa/48 kDa

ID gène: 5701

UniProt: P35998

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway