TSG101 anticorps

N° du produit ABIN7260319

Détail du produit anti-TSG101 anticorps

Antigène: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TSG101 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: A synthetic peptide of human TSG101 (NP_006283.1).

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200 IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TSG101

Antigène: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Autre désignation: TSG101 (TSG101 Produits)

Synonymes: anticorps CG9712, anticorps DmTSG101, anticorps Dmel\\CG9712, anticorps ESCRT-I, anticorps Tsg101, anticorps burs, anticorps dTSg101, anticorps dTsg101, anticorps dVps23, anticorps ept, anticorps tsg101, anticorps vps23, anticorps TSG101, anticorps MGC76193, anticorps TSG10, anticorps VPS23, anticorps AI255943, anticorps CC2, anticorps Rw, anticorps zgc:86926, anticorps tumor susceptibility 101, anticorps Tumor susceptibility gene 101, anticorps Tumor Susceptibility Gene homolog, anticorps tumor susceptibility gene 101, anticorps tumor susceptibility 101a, anticorps tumor susceptibility 101 L homeolog, anticorps TSG101, anticorps tsg-101, anticorps tsg101, anticorps Tsg101, anticorps tsg101a, anticorps tsg101.L

Sujet: The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.

ID gène: 7251

UniProt: Q99816