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HBEGF anticorps (AA 51-150)

HBEGF Reactivité: Humain, Souris, Rat ELISA, IF (cc), IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN701050
  • Antigène Voir toutes HBEGF Anticorps
    HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))
    Épitope
    • 15
    • 14
    • 14
    • 8
    • 7
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-150
    Reactivité
    • 76
    • 19
    • 18
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 69
    • 10
    Lapin
    Clonalité
    • 66
    • 12
    • 1
    Polyclonal
    Conjugué
    • 27
    • 10
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp HBEGF est non-conjugé
    Application
    • 36
    • 28
    • 25
    • 15
    • 13
    • 11
    • 8
    • 7
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain, Souris, Rat
    Homologie
    Dog,Cow,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human HB-EGF/DTSF
    Isotype
    IgG
  • Indications d'application
    ELISA 1:500-1000
    IHC-P 1:200-400
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Lebkuechner, Wilhelmsson, Möllerström, Pekna, Pekny: "Heterogeneity of Notch signaling in astrocytes and the effects of GFAP and vimentin deficiency." dans: Journal of neurochemistry, (2015) (PubMed).

  • Antigène
    HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))
    Autre désignation
    HB-EGF (HBEGF Produits)
    Synonymes
    anticorps hbegf, anticorps zgc:165443, anticorps HBEGF, anticorps zgc:175091, anticorps DTR, anticorps DTS, anticorps DTSF, anticorps HEGFL, anticorps Dtr, anticorps GFHB, anticorps Hb-egf, anticorps Hegfl, anticorps AW047313, anticorps Dts, anticorps HB-EGF, anticorps heparin-binding EGF-like growth factor b, anticorps heparin binding EGF like growth factor, anticorps Heparin-binding EGF-like growth factor, anticorps heparin-binding EGF-like growth factor a, anticorps heparin-binding EGF-like growth factor, anticorps hbegfb, anticorps HBEGF, anticorps hbegf, anticorps hbegfa, anticorps Hbegf
    Sujet

    Synonyms: DTR, DTS, DTSF, HEGFL, Proheparin-binding EGF-like growth factor, HBEGF

    Background: Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.

    ID gène
    1839
    UniProt
    Q99075
    Pathways
    Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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