SLC11A2 anticorps (AA 251-350)

N° du produit ABIN701065

Détail du produit anti-SLC11A2 anticorps

Antigène: SLC11A2 (Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 2 (SLC11A2))

Épitope: AA 251-350

Reactivité: Humain, Souris, Rat, Poulet

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC11A2 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Poulet, Humain, Souris, Rat

Homologie: Cow

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SLC11A2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-SLC11A2 (ABIN701065)

Zhang, Li, Liao, Zhang, Lu, Luo: "Effect of iron source on iron absorption and gene expression of iron transporters in the ligated duodenal loops of broilers." dans: Journal of animal science, Vol. 95, Issue 4, pp. 1587-1597, (2017) (PubMed).

Zhang, Zhao, Chang, Zhang, Chu, Zhang, Liu, Guo, Wang, Gao, Zhang, Chu: "Calcium channel blockers ameliorate iron overload-associated hepatic fibrosis by altering iron transport and stellate cell apoptosis." dans: Toxicology and applied pharmacology, Vol. 301, pp. 50-60, (2016) (PubMed).

Détails sur SLC11A2

Antigène: SLC11A2 (Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 2 (SLC11A2))

Autre désignation: SLC11A2 (SLC11A2 Produits)

Synonymes: anticorps DCT1, anticorps DMT1, anticorps NRAMP2, anticorps Nramp2, anticorps mk, anticorps van, anticorps Dmt1, anticorps ATNRAMP2, anticorps F8G22.4, anticorps F8G22_4, anticorps NRAMP metal ion transporter 2, anticorps dct1, anticorps dmt1, anticorps nramp2, anticorps SLC11A2, anticorps cb426, anticorps fa07b10, anticorps wu:fa07b10, anticorps zgc:136699, anticorps solute carrier family 11 member 2, anticorps solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2, anticorps NRAMP metal ion transporter 2, anticorps manganese transport protein, anticorps metal transporter Nramp2, anticorps solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2, anticorps SLC11A2, anticorps Slc11a2, anticorps NRAMP2, anticorps LOC9327403, anticorps slc11a2

Sujet:

Synonyms: DCT1, DMT1, NRAMP2, Natural resistance-associated macrophage protein 2, NRAMP 2, Divalent cation transporter 1, Divalent metal transporter 1, DMT-1, Solute carrier family 11 member 2, SLC11A2, OK/SW-cl.20

Background: Important in metal transport, in particular iron. Can also transport manganese, cobalt, cadmium, nickel, vanadium and lead. Involved in apical iron uptake into duodenal enterocytes. Involved in iron transport from acidified endosomes into the cytoplasm of erythroid precursor cells. May play an important role in hepatic iron accumulation and tissue iron distribution. May serve to import iron into the mitochondria.

ID gène: 4891

UniProt: P49281

Pathways: Transition Metal Ion Homeostasis, Proton Transport, Positive Regulation of Endopeptidase Activity