RFC5 anticorps

N° du produit ABIN7264105

Détail du produit anti-RFC5 anticorps

Antigène: RFC5 (Replication Factor C (Activator 1) 5, 36.5kDa (RFC5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RFC5 est non-conjugé

Application: Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human RFC5 (NP_031396.1).

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RFC5

Antigène: RFC5 (Replication Factor C (Activator 1) 5, 36.5kDa (RFC5))

Autre désignation: RFC5 (RFC5 Produits)

Synonymes: anticorps zgc:110313, anticorps 2610020K06Rik, anticorps 2610209F07Rik, anticorps 36.5kDa, anticorps 36kDa, anticorps Recc5, anticorps RFC36, anticorps replication factor C (activator 1) 5, anticorps replication factor C subunit 5, anticorps replication factor C subunit 5 L homeolog, anticorps rfc5, anticorps Rfc5, anticorps RFC5, anticorps rfc5.L

Sujet: The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 36 kD subunit. This subunit can interact with the C-terminal region of PCNA. It forms a core complex with the 38 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 9.

ID gène: 5985

UniProt: P40937

Pathways: Telomere Maintenance, Réparation de l'ADN, DNA Replication, Synthesis of DNA