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CLEC9A anticorps

CLEC9A Reactivité: Humain FACS, ICC Hôte: Souris Monoclonal 8F9 unconjugated
N° du produit ABIN7013959
  • Antigène Voir toutes CLEC9A Anticorps
    CLEC9A (C-Type Lectin Domain Family 9, Member A (CLEC9A))
    Reactivité
    • 51
    • 37
    • 15
    Humain
    Hôte
    • 52
    • 13
    • 4
    • 2
    Souris
    Clonalité
    • 55
    • 15
    • 1
    Monoclonal
    Conjugué
    • 24
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp CLEC9A est non-conjugé
    Application
    • 55
    • 26
    • 26
    • 14
    • 13
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Specificité
    The mouse monoclonal antibody 8F9 recognizes an extracellular epitope of CD370 / CLEC9A (DNGR1), a type II transmembrane protein functioning as an endocytic receptor on BDCA31+ dendritic cells and on a subset of CD14+ CD16- monocytes.
    Purification
    Purified by protein-A affinity chromatography.
    Immunogène
    RBL-2H3 cells expressing human CLEC9A fused to an HA epitope
    Clone
    8F9
    Isotype
    IgG2a
    Top Product
    Discover our top product CLEC9A Anticorps primaire
  • Indications d'application
    Flow cytometry: Recommended dilution: 1-4 μg/mL
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Do not freeze.
  • Antigène
    CLEC9A (C-Type Lectin Domain Family 9, Member A (CLEC9A))
    Autre désignation
    CD370 (CLEC9A Produits)
    Synonymes
    anticorps 9830005G06Rik, anticorps DNGR-1, anticorps DNGR1, anticorps UNQ9341, anticorps RGD1562513, anticorps C-type lectin domain family 9, member a, anticorps C-type lectin domain containing 9A, anticorps C-type lectin domain family 9, member A, anticorps Clec9a, anticorps CLEC9A
    Sujet
    C-type lectin domain containing 9A,CD370 / CLEC9A, also known as DNGR1, is a type II transmembrane glycoprotein with extracellular C-type lectin domain and intracellular ITAM-containing domain. Its expression is restricted to BDCA3+ conventional dendritic cells and to a subset of CD14+ CD16- monocytes. CD370 serves as a receptor for ubiquitous preformed acid-labile protein associated ligands that are exposed when the cell membrane is damaged, such as on necrotic cells. Its triggering by these ligands mediates recruitment and activation of the tyrosine kinase Syk and leads to their cross-presentation to the immune system.,CLEC9A, DNGR1, DNGR-1, UNQ9341
    ID gène
    283420
    UniProt
    Q6UXN8
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