GEMIN4 anticorps

N° du produit ABIN7114526

Détail du produit anti-GEMIN4 anticorps

Antigène: GEMIN4 (Gem (Nuclear Organelle) Associated Protein 4 (GEMIN4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GEMIN4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: gem(nuclear organelle) associated protein 4

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur GEMIN4

Antigène: GEMIN4 (Gem (Nuclear Organelle) Associated Protein 4 (GEMIN4))

Autre désignation: GEMIN4 (GEMIN4 Produits)

Synonymes: anticorps HC56, anticorps HCAP1, anticorps HHRF-1, anticorps p97, anticorps 4932415L08Rik, anticorps AU015359, anticorps im:7143815, anticorps wu:fc41c09, anticorps zgc:110169, anticorps GEMIN4, anticorps RGD1563715, anticorps gem nuclear organelle associated protein 4, anticorps gem (nuclear organelle) associated protein 4, anticorps GEMIN4, anticorps Gemin4, anticorps gemin4

Sujet: Synonyms: Background:The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins(snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.

Poids moléculaire: 120-130 kDa

ID gène: 50628

UniProt: P57678

Pathways: Ribonucleoprotein Complex Subunit Organization