GNAI1 anticorps
-
- Antigène Voir toutes GNAI1 Anticorps
- GNAI1 (Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1))
-
Reactivité
- Humain, Souris, Rat
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp GNAI1 est non-conjugé
-
Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
- Purification
- Immunogen affinity purified
- Pureté
- ≥95 % as determined by SDS-PAGE
- Immunogène
- guanine nucleotide binding protein(G protein), alpha inhibiting activity polypeptide 1
- Isotype
- IgG
- Top Product
- Discover our top product GNAI1 Anticorps primaire
-
-
- Indications d'application
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Date de péremption
- 12 months
-
- Antigène
- GNAI1 (Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1))
- Autre désignation
- GNAI1 (GNAI1 Produits)
- Synonymes
- anticorps AU046200, anticorps Gialpha1, anticorps Gnai-1, anticorps gnai1, anticorps Gi, anticorps BPGTPB, anticorps zgc:63957, anticorps guanine nucleotide binding protein (G protein), alpha inhibiting 1, anticorps G protein subunit alpha i1, anticorps guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 S homeolog, anticorps guanine nucleotide-binding protein G(i) subunit alpha-1, anticorps guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1, anticorps Gnai1, anticorps gnai1.S, anticorps GNAI1, anticorps LOC397505, anticorps gnai1
- Sujet
- Synonyms: Background:Guanine nucleotide-binding proteins(G proteins) function as transducers downstream of G protein-coupled receptors(GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numerous regulatory proteins(PubMed:8774883, PubMed:18434541). Signaling is mediated via effector proteins, such as adenylate cyclase. Inhibits adenylate cyclase activity, leading to decreased intracellular cAMP levels(By similarity). The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. Required for normal cytokinesis during mitosis(PubMed:17635935).
- Poids moléculaire
- 40 kDa
- ID gène
- 2770
- UniProt
- P63096
- Pathways
- G-protein mediated Events
-