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OSBPL3 anticorps

OSBPL3 Reactivité: Humain, Souris, Rat WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7117176
  • Antigène Voir toutes OSBPL3 Anticorps
    OSBPL3 (Oxysterol Binding Protein-Like 3 (OSBPL3))
    Reactivité
    • 18
    • 17
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 20
    • 2
    • 1
    Lapin
    Clonalité
    • 23
    Polyclonal
    Conjugué
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp OSBPL3 est non-conjugé
    Application
    • 13
    • 13
    • 7
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    Immunogen affinity purified
    Pureté
    ≥95 % as determined by SDS-PAGE
    Immunogène
    oxysterol binding protein-like 3
    Isotype
    IgG
    Top Product
    Discover our top product OSBPL3 Anticorps primaire
  • Indications d'application
    WB: 1:500-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Date de péremption
    12 months
  • Antigène
    OSBPL3 (Oxysterol Binding Protein-Like 3 (OSBPL3))
    Autre désignation
    OSBPL3 (OSBPL3 Produits)
    Synonymes
    anticorps osbpl3, anticorps zgc:101089, anticorps OSBPL3, anticorps ORP-3, anticorps ORP3, anticorps OSBP3, anticorps 1200014M06Rik, anticorps 6720421I08Rik, anticorps A530055M08, anticorps RGD1564287, anticorps oxysterol binding protein like 3, anticorps oxysterol binding protein-like 3a, anticorps oxysterol binding protein-like 3, anticorps OSBPL3, anticorps osbpl3a, anticorps osbpl3, anticorps Osbpl3
    Sujet
    Synonyms:KIAA0704, ORP3, OSBP3 Background:Phosphoinositide-binding protein which associates with both cell and endoplasmic reticulum(ER) membranes(PubMed:16143324). Can bind to the ER membrane protein VAPA and recruit VAPA to plasma membrane sites, thus linking these intracellular compartments(PubMed:25447204). The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1(ITGB1) activation at the cell surface(PubMed:18270267, PubMed:25447204). With VAPA, may regulate ER morphology(PubMed:16143324). Has a role in regulation of the actin cytoskeleton, cell polarity and cell adhesion(PubMed:18270267). Binds to phosphoinositides with preference for PI(3,4)P2 and PI(3,4,5)P3(PubMed:16143324). Also binds 25-hydroxycholesterol and cholesterol(PubMed:17428193).
    Poids moléculaire
    101 kDa
    ID gène
    26031
    UniProt
    Q9H4L5
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