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STAM2 anticorps
STAM2
Reactivité: Humain, Souris, Rat
WB, ELISA, IP
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN7119091
Détail du produit anti-STAM2 anticorps
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Antigène
Voir toutes STAM2 Anticorps
STAM2
(Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2))
Reactivité
Humain, Souris, Rat
Hôte
Toutes les hôtes sur STAM2 Anticorps
Lapin
Clonalité
Toutes les clonalités sur STAM2 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers STAM2 Anticorps
Cet anticorp STAM2 est non-conjugé
Application
Tous les applications à travers STAM2 Anticorps.
Western Blotting (WB), ELISA, Immunoprecipitation (IP)
Purification
Immunogen affinity purified
Pureté
≥95 % as determined by SDS-PAGE
Immunogène
signal transducing adaptor molecule(SH3 domain and ITAM motif) 2
Isotype
IgG
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Information d'application
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Indications d'application
WB: 1:500-1:2000, IP: 1:200-1:2000
Restrictions
For Research Use only
Stockage
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Date de péremption
12 months
Détails sur STAM2
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Antigène
STAM2
(Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2))
Autre désignation
STAM2 (STAM2 Produits )
Synonymes
anticorps Hbp, anticorps STAM2A, anticorps STAM2B, anticorps 1200004O12Rik, anticorps 5730456G07Rik, anticorps BB145015, anticorps stam2, anticorps MGC52950, anticorps zgc:103628, anticorps signal transducing adaptor molecule 2, anticorps signal transducing adaptor molecule (SH3 domain and ITAM motif) 2, anticorps signal transducing adaptor molecule 2 S homeolog, anticorps STAM2, anticorps Stam2, anticorps stam2.S, anticorps stam2
Sujet
Synonyms:HBP Background:Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body(MVBs) when complexed with HGS(ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes(By similarity).
Poids moléculaire
68 kDa
ID gène
10254
UniProt
O75886
Pathways
EGFR Signaling Pathway , EGFR Downregulation
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