DnaJ (Hsp40) Homolog, Subfamily B, Member 6 (DNAJB6) anticorps

Détails pour le produit réf. ABIN708146
Antigène
  • DJ4
  • DnaJ
  • HHDJ1
  • HSJ-2
  • HSJ2
  • LGMD1E
  • MRJ
  • MSJ-1
  • Mrj
  • mDj4
  • dnajb6
  • zgc:56709
  • hsj2
  • DnaJ heat shock protein family (Hsp40) member B6
  • DnaJ (Hsp40) homolog, subfamily B, member 6b
  • DnaJ heat shock protein family (Hsp40) member B6 S homeolog
  • DnaJ heat shock protein family (Hsp40) member B6 L homeolog
  • DNAJB6
  • Dnajb6
  • dnajb6b
  • dnajb6.S
  • dnajb6.L
Reactivité
Humain, Souris, Rat (Rattus)
78
15
14
7
3
2
2
2
1
1
1
1
1
1
1
1
Hôte
Lapin
65
16
7
Clonalité
Polyclonal
Conjugué
Inconjugué
5
5
4
4
4
3
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
71
39
35
24
23
10
7
4
4
3
2
1
Options
Immunogène KLH conjugated synthetic peptide derived from human HSJ2/DNAJB6
Isotype IgG
Purification Purified by Protein A.
Antigène
Autre désignation Dnajb6 (DNAJB6 Antibody Extrait)
Sujet

Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Reduces huntingtin aggregation associated with HD. Also reduces cellular toxicity and caspase-3 activity.

Synonyms: DJ4, DnaJ, DNAJ B6, DnaJ homolog subfamily B member 6, DNAJB6, DNJB6_HUMAN, Heat shock protein J2, HHDJ1, HSJ-2, HSJ2, MRJ, MSJ-1, MSJ1.

ID gène 10049
Indications d'application WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Stock -20 °C
Stockage commentaire Store at -20°C
Date de péremption 12 months
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