Pyruvate Carboxylase (PC) anticorps (Cy3)

Détails pour le produit réf. ABIN708179
Antigène
  • BcDNA
  • BcDNA:GH06348
  • Dmel\\CG1516
  • PC
  • pyc
  • wu:fb82g08
  • wu:fj85g01
  • PCX
  • BA4157
  • Pc
  • Pcb
  • PCB
  • Pcx
  • Pyruvate carboxylase
  • pyruvate carboxylase b
  • PYruvate Carboxylase
  • pyruvate carboxylase
  • pyruvate carboxylase Pyr1
  • PCB
  • pcxb
  • pyc-1
  • PC
  • pyc
  • pyr1
  • CNF00650
  • PYC1
  • Ndas_1152
  • Ilyop_2503
  • Calni_0495
  • Ftrac_1004
  • Plabr_3574
  • Sgly_2936
  • Celly_0558
  • Hipma_0131
  • Halhy_1567
  • Mesop_1269
  • Pcx
  • Pc
Reactivité
Humain, Souris, Rat (Rattus)
44
36
26
4
4
3
3
3
3
3
2
1
1
1
Hôte
Lapin
46
7
2
Clonalité
Polyclonal
Conjugué
Cy3
4
4
3
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
43
28
18
12
10
4
3
3
3
2
2
1
1
Options
Immunogène KLH conjugated synthetic peptide derived from human PCB
Isotype IgG
Purification Purified by Protein A.
Antigène
Autre désignation PCB (PC Antibody Extrait)
Sujet

PCB (Pyruvate carboxylase) requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. PCB is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene.

Synonyms: mitochondrial, OTTHUMP00000235155, OTTHUMP00000235156, PC, PCB, Pcx, PYC_HUMAN, Pyruvate carboxylase, Pyruvate carboxylase mitochondrial, Pyruvic carboxylase.

ID gène 5091
Indications d'application IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months
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