Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

Recombinant RNF2 anticorps

RNF2 Reactivité: Humain WB, ELISA, IHC, IF Hôte: Lapin Monoclonal 2H12 unconjugated Recombinant Antibody
N° du produit ABIN7127796
  • Antigène Voir toutes RNF2 Anticorps
    RNF2 (Ring Finger Protein 2 (RNF2))
    Type d'anticorp
    Recombinant Antibody
    Reactivité
    • 48
    • 28
    • 21
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    Humain
    Hôte
    • 39
    • 7
    • 2
    • 1
    Lapin
    Clonalité
    • 39
    • 10
    Monoclonal
    Conjugué
    • 36
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp RNF2 est non-conjugé
    Application
    • 35
    • 18
    • 11
    • 10
    • 9
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
     Réactivité croisée
    Humain
    Purification
    Affinity-chromatography
    Immunogène
    A synthesized peptide derived from human RNF20
    Clone
    2H12
    Isotype
    IgG
    Top Product
    Discover our top product RNF2 Anticorps primaire
  • Indications d'application
    Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    RNF2 (Ring Finger Protein 2 (RNF2))
    Autre désignation
    RNF2 (RNF2 Produits)
    Synonymes
    anticorps BAP-1, anticorps BAP1, anticorps DING, anticorps HIPI3, anticorps RING1B, anticorps RING2, anticorps AI326319, anticorps AI450156, anticorps AU019207, anticorps Ring1B, anticorps dinG, anticorps fa19h05, anticorps ring1b, anticorps wu:fa19h05, anticorps wz4556, anticorps bap-1, anticorps bap1, anticorps ding, anticorps hipi3, anticorps ring2, anticorps ring finger protein 2, anticorps ring finger protein 2 L homeolog, anticorps RNF2, anticorps Rnf2, anticorps rnf2, anticorps rnf2.L
    Sujet

    Background: Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role inb histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B, reports about the cooperation with UBE2E1/UBCH are contradictory. Required for transcriptional activation of Hox genes. Recruited to the MDM2 promoter, probably by being recruited by p53/TP53, and thereby acts as a transcriptional coactivator. Mediates the polyubiquitination of isoform 2 of PA2G4 in cancer cells leading to its proteasome-mediated degradation.

    Aliases: E3 ubiquitin-protein ligase BRE1A (BRE1-A) (hBRE1) (EC 2.3.2.27) (RING finger protein 20) (RING-type E3 ubiquitin transferase BRE1A), RNF20, BRE1A

    UniProt
    Q5VTR2
Vous êtes ici: