Bile Acid CoA: Amino Acid N-Acyltransferase (Glycine N-Choloyltransferase) (BAAT) (AA 110-160) anticorps (HRP)

Détails pour le produit réf. ABIN708785
Antigène
  • BACAT
  • BAT
  • AI118337
  • AI158864
  • kan-1
  • BAAT
  • bile acid-CoA:amino acid N-acyltransferase
  • Bile acid-CoA:amino acid N-acyltransferase
  • bile acid-Coenzyme A: amino acid N-acyltransferase
  • bile acid CoA:amino acid N-acyltransferase
  • BAAT
  • RPIC_RS10270
  • Bcav_2277
  • Rpic12D_1765
  • Baat
  • LOC481635
  • LOC100054567
  • LOC786798
Épitope
AA 110-160
14
5
4
3
1
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
56
31
22
2
2
1
1
1
Hôte
Lapin
52
5
Clonalité
Polyclonal
Conjugué
HRP
3
2
2
2
2
2
2
2
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
35
23
13
12
4
1
1
1
Options
Immunogène KLH conjugated synthetic peptide derived from human BAAT
Isotype IgG
Purification Purified by Protein A.
Antigène
Autre désignation Baat (BAAT Antibody Extrait)
Sujet

Involved in bile acid metabolism. In liver hepatocytes catalyzes the second step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi. The major components of bile are cholic acid and chenodeoxycholic acid. In a first step the bile acids are converted to an acyl-CoA thioester, either in peroxisomes (primary bile acids deriving from the cholesterol pathway), or cytoplasmic at the endoplasmic reticulum (secondary bile acids). May catalyze the conjugation of primary or secondary bile acids, or both. The conjugation increases the detergent properties of bile acids in the intestine, which facilitates lipid and fat-soluble vitamin absorption. In turn, bile acids are deconjugated by bacteria in the intestine and are recycled back to the liver for reconjugation (secondary bile acids). May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids. In vitro, catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH), and conjugates glycine to these acyl-CoAs.

Subcellular location: Cytoplasm

Synonyms: BAT, BACAT, Bile acid-CoA:amino acid N-acyltransferase, Glycine N-choloyltransferase, Long-chain fatty-acyl-CoA hydrolase, BAAT

ID gène 570
UniProt Q14032
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months
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