TMEM123 anticorps

N° du produit ABIN7131392

Détail du produit anti-TMEM123 anticorps

Antigène: TMEM123 (Transmembrane Protein 123 (TMEM123))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TMEM123 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: Antigen affinity purification

Immunogène: Fusion protein of Human TMEM123

Isotype: IgG

Information d'application

Indications d'application: ELISA:1:2000-1:10000, IHC:1:30-1:150,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur TMEM123

Antigène: TMEM123 (Transmembrane Protein 123 (TMEM123))

Autre désignation: TMEM123 (TMEM123 Produits)

Synonymes: anticorps KCT3, anticorps PORIMIN, anticorps PORMIN, anticorps 2310075C12Rik, anticorps RGD1305625, anticorps kct3, anticorps pormin, anticorps porimin, anticorps transmembrane protein 123, anticorps transmembrane protein 123 L homeolog, anticorps TMEM123, anticorps Tmem123, anticorps tmem123.L, anticorps tmem123

Sujet:

Background: This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death.

Aliases: TMEM123 antibody, KCT3 antibody, PSEC0111 antibody, UNQ641/PRO1271 antibody, Porimin antibody, Keratinocytes-associated transmembrane protein 3 antibody, KCT-3 antibody, Pro-oncosis receptor inducing membrane injury antibody, Transmembrane protein 123 antibody

UniProt: Q8N131

Pathways: Regulation of Cell Size