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PKC delta anticorps (pSer645)

PKCd Reactivité: Humain WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7138674
  • Antigène Voir toutes PKC delta (PKCd) Anticorps
    PKC delta (PKCd) (Protein Kinase C, delta (PKCd))
    Épitope
    • 22
    • 20
    • 19
    • 16
    • 15
    • 15
    • 15
    • 14
    • 11
    • 8
    • 8
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer645
    Reactivité
    • 209
    • 154
    • 152
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 218
    • 11
    Lapin
    Clonalité
    • 207
    • 22
    Polyclonal
    Conjugué
    • 93
    • 15
    • 13
    • 11
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    Cet anticorp PKC delta est non-conjugé
    Application
    • 164
    • 90
    • 81
    • 80
    • 49
    • 47
    • 36
    • 23
    • 22
    • 13
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
    Immunogène
    Peptide sequence around phosphorylation site of serine 645 (R-L-S(p)-Y-S) derived from Human PKCd.
    Isotype
    IgG
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    Discover our top product PKCd Anticorps primaire
  • Indications d'application
    WB:1:500-1:1000, IHC:1:50-1:100,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    PKC delta (PKCd) (Protein Kinase C, delta (PKCd))
    Autre désignation
    PRKCD (PKCd Produits)
    Synonymes
    anticorps MAY1, anticorps PKCD, anticorps nPKC-delta, anticorps AI385711, anticorps D14Ertd420e, anticorps PKC[d], anticorps PKCdelta, anticorps Pkcd, anticorps fb09d10, anticorps fv43b11, anticorps prkcd, anticorps wu:fb09d10, anticorps wu:fv43b11, anticorps zgc:56558, anticorps PKC-delta, anticorps may1, anticorps npkc-delta, anticorps pkc-delta2, anticorps pkcd, anticorps tpa-1, anticorps protein kinase C delta, anticorps protein kinase C, delta, anticorps protein kinase C, delta a, anticorps protein kinase C delta L homeolog, anticorps PRKCD, anticorps Prkcd, anticorps prkcda, anticorps prkcd.L, anticorps prkcd
    Sujet

    Background: This is calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. May play a role in antigen-dependent control of B-cell function. Phosphorylates MUC1 in the C-terminal and regulates the interaction between MUC1 and beta-catenin.

    Kei Sakamoto, et,al. (2003) Am J Physiol Endocrinol Metab , 285: E1081 - E1088.
    Ling Zhang, et,al. (2004) J. Biol. Chem , 279: 28315 - 28319.
    Kristof Van Kolen et,al. (2006) FEBS J , 273: 1843 - 1854.
    Martin Villalba, et,al. (2002) J. Cell Biol , 157: 253.

    Aliases: CVID9 antibody, D14Ertd420e antibody, Kinase PKC delta antibody, KPCD antibody, KPCD_HUMAN antibody, MAY 1 antibody, MAY1 antibody, MGC49908 antibody, nPKC delta antibody, nPKC-delta antibody, PCKd antibody, PKC d antibody, PKC delta antibody, PKCD antibody, PKCdelta antibody, PRKC D antibody, PRKC delta antibody, Prkcd antibody, Protein Kinase C delta antibody, Protein kinase C delta type antibody, Protein kinase C delta VIII antibody, Protein Kinase Cdelta antibody, Tyrosine protein kinase PRKCD antibody

    UniProt
    Q05655
    Pathways
    Interferon-gamma Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Dicarboxylic Acid Transport, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, Lipid Metabolism
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