PKC theta anticorps (pSer676)
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- Antigène Voir toutes PKC theta (PRKCQ) Anticorps
- PKC theta (PRKCQ) (Protein Kinase C, theta (PRKCQ))
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Épitope
- pSer676
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PKC theta est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
- Réactivité croisée
- Humain, Souris, Rat
- Purification
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- Immunogène
- Peptide sequence around phosphorylation site of serine 676 (R-L-S(p)-F-A) derived from Human PKCth.
- Isotype
- IgG
- Top Product
- Discover our top product PRKCQ Anticorps primaire
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- Indications d'application
- WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- PKC theta (PRKCQ) (Protein Kinase C, theta (PRKCQ))
- Autre désignation
- PRKCQ (PRKCQ Produits)
- Synonymes
- anticorps PRKCT, anticorps nPKC-theta, anticorps A130035A12Rik, anticorps AW494342, anticorps PKC-0, anticorps PKC-theta, anticorps PKCtheta, anticorps Pkcq, anticorps protein kinase C theta, anticorps protein kinase C eta, anticorps protein kinase C, theta, anticorps PRKCQ, anticorps PRKCH, anticorps Prkcq
- Sujet
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Background:
This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Essential for T-cell receptor (TCR)-mediated T-cell activation, but is dispensable during TCR-dependent thymocyte development. Links the TCR signaling complex to the activation of NF-kappa-B in mature T lymphocytes. Required for interleukin-2 (IL2) production.
Kristof Van Kolen, et al. (2006) FEBS J , 273: 1843 - 1854.
Martin Villalba, et al. (2002) J. Cell Biol , 157: 253.
Jie Zhang, et al. (2004) J. Biol. Chem , 279: 22118 - 22123.
Castro AF, et al. (1998) Am J Physiol Cell Physiol, 275: C113 - C119.Aliases: KPCT_HUMAN antibody, MGC126514 antibody, MGC141919 antibody, nPKC theta antibody, nPKC-theta antibody, nPKCtheta antibody, OTTHUMP00000043364 antibody, OTTHUMP00000043365 antibody, PKC 0 antibody, PKC0 antibody, Prkcq antibody, PRKCT antibody, Protein kinase C theta antibody, Protein kinase C theta type antibody, Protein Kinase Ctheta antibody
- UniProt
- Q04759
- Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling
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