BCR anticorps (pTyr177)

N° du produit ABIN7138949

Détail du produit anti-BCR anticorps

Antigène: BCR (Breakpoint Cluster Region (BCR))

Épitope: pTyr177

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCR est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain, Souris

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogène: Peptide sequence around phosphorylation site of tyrosine 177 (P-F-Y(p)-V-N) derived from Human Bcr.

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:1000, IHC:1:50-1:100,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur BCR

Antigène: BCR (Breakpoint Cluster Region (BCR))

Autre désignation: BCR (BCR Produits)

Synonymes: anticorps si:dkey-83d9.7, anticorps zK83D9.7, anticorps BCR, anticorps ALL, anticorps BCR1, anticorps CML, anticorps D22S11, anticorps D22S662, anticorps PHL, anticorps 5133400C09Rik, anticorps AI561783, anticorps AI853148, anticorps mKIAA3017, anticorps breakpoint cluster region, anticorps BCR, RhoGEF and GTPase activating protein, anticorps bcr, anticorps BCR, anticorps Bcr

Sujet:

Background: GTPase-activating protein for RAC1 and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. Displays serine/threonine kinase activity.

Sattler M, et al. Mol Cell Biol. 1999 Nov, 19(11): 7473-7480.
Li S et al. EMBO J. 2001 Dec 3, 20(23): 6793-6804.
Million RP, et,al. Mol Cell Biol. 2004 Jun, 24(11): 4685-4695.
Malcolm A. Meyn, et al. . Biol. Chem., Oct 2006, 281: 30907

Aliases: ALL antibody, bcr antibody, BCR/ABL FUSION GENE, INCLUDED antibody, BCR/FGFR1 chimera protein antibody, BCR/FGFR1 FUSION GENE, INCLUDED antibody, BCR/PDGFRA FUSION GENE, INCLUDED antibody, BCR_HUMAN antibody, BCR1 antibody, Breakpoint cluster region antibody, Breakpoint cluster region protein antibody, CML antibody, D22S11 antibody, D22S662 antibody, FGFR1/BCR chimera protein antibody, PHL antibody, Renal carcinoma antigen NY-REN-26 antibody

UniProt: P11274

Pathways: Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling