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TNK2 anticorps (pTyr284)

TNK2 Reactivité: Humain WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7138968
  • Antigène Voir toutes TNK2 Anticorps
    TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))
    Épitope
    • 21
    • 15
    • 13
    • 9
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr284
    Reactivité
    • 122
    • 51
    • 46
    • 3
    • 2
    • 2
    Humain
    Hôte
    • 119
    • 3
    • 1
    Lapin
    Clonalité
    • 121
    • 1
    Polyclonal
    Conjugué
    • 49
    • 11
    • 11
    • 9
    • 8
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp TNK2 est non-conjugé
    Application
    • 95
    • 68
    • 26
    • 26
    • 25
    • 20
    • 16
    • 11
    • 8
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
     Réactivité croisée
    Humain, Souris
    Purification
    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
    Immunogène
    Peptide sequence around phosphorylation site of tyrosine 284 (D-H-Y(p)-V-M) derived from Human ACK1.
    Isotype
    IgG
    Top Product
    Discover our top product TNK2 Anticorps primaire
  • Indications d'application
    WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))
    Autre désignation
    TNK2 (TNK2 Produits)
    Synonymes
    anticorps ACK, anticorps ACK-1, anticorps ACK1, anticorps p21cdc42Hs, anticorps AW552477, anticorps Ack, anticorps Cdgip, anticorps Pyk1, anticorps ack1, anticorps ackb, anticorps tnk2, anticorps tnk2b, anticorps wu:fj16g04, anticorps zgc:154019, anticorps tyrosine kinase non receptor 2, anticorps tyrosine kinase, non-receptor, 2, anticorps tyrosine kinase, non-receptor, 1, anticorps TNK2, anticorps Tnk2, anticorps tnk1
    Sujet

    Background:

    Non-receptor tyrosine-protein and serine/threonine-protein kinase that is implicated in cell spreading and migration, cell survival, cell growth and proliferation. Transduces extracellular signals to cytosolic and nuclear effectors. Phosphorylates AKT1, AR, MCF2, WASL and WWOX. Implicated in trafficking and clathrin-mediated endocytosis through binding to epidermal growth factor receptor (EGFR) and clathrin. Binds to both poly- and mono-ubiquitin and regulates ligand-induced degradation of EGFR, thereby contributing to the accumulation of EGFR at the limiting membrane of early endosomes.

    Manser E., Nature 363:364-367(1993).
    Ota T., Nat. Genet. 36:40-45(2004).
    Eisenmann K.M., Nat. Cell Biol. 1:507-513(1999)

    Aliases: Acetate kinase 1 antibody, Acetokinase 1 antibody, ACK 1 antibody, ACK antibody, ACK-1 antibody, ACK1 antibody, ACK1_HUMAN antibody, Activated Cdc42 associated kinase 1 antibody, Activated CDC42 kinase 1 antibody, Activated p21cdc42Hs kinase antibody, FLJ44758 antibody, FLJ45547 antibody, p21cdc42Hs antibody, TNK 2 antibody, TNK2 antibody, Tyrosine kinase non receptor 2 antibody, Tyrosine kinase non receptor protein 2 antibody, Tyrosine kinase non-receptor protein 2 antibody

    UniProt
    Q07912
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