PRKAB1 anticorps (AA 1-270)

N° du produit ABIN7142664

Détail du produit anti-PRKAB1 anticorps

Antigène: PRKAB1 (Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1))

Épitope: AA 1-270

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRKAB1 est non-conjugé

Application: ELISA, Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human 5\'-AMP-activated protein kinase subunit beta-1 protein (1-270AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PRKAB1

Antigène: PRKAB1 (Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1))

Autre désignation: PRKAB1 (PRKAB1 Produits)

Synonymes: anticorps AMPK, anticorps HAMPKb, anticorps 1300015D22Rik, anticorps AU021155, anticorps E430008F22, anticorps MGC82489, anticorps prkab1, anticorps wu:fk93d05, anticorps wu:fw87e09, anticorps zgc:56652, anticorps zgc:76975, anticorps zgc:92228, anticorps protein kinase AMP-activated non-catalytic subunit beta 1, anticorps protein kinase, AMP-activated, beta 1 non-catalytic subunit, anticorps protein kinase, AMP-activated, beta 1 non-catalytic subunit S homeolog, anticorps protein kinase, AMP-activated, beta 1 non-catalytic subunit, b, anticorps protein kinase, AMP-activated, beta 1 non-catalytic subunit, a, anticorps PRKAB1, anticorps Prkab1, anticorps prkab1.S, anticorps prkab1, anticorps prkab1b, anticorps prkab1a

Sujet:

Background: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton, probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

Aliases: 1300015D22Rik antibody, 5''-AMP-activated protein kinase subunit beta-1 antibody, 5'-AMP-activated protein kinase beta-1 subunit antibody, AAKB1_HUMAN antibody, AMP-activated protein kinase beta subunit antibody, AMP-ACTIVATED PROTEIN KINASE, NONCATALYTIC, BETA-1 antibody, AMP-activated, noncatalytic, beta-1 antibody, AMPK antibody, AMPK beta 1 chain antibody, AMPK subunit beta-1 antibody, AMPK-BETA-1 antibody, AMPKb antibody, AU021155 antibody, E430008F22 antibody, HAMPKb antibody, MGC17785 antibody, PRKAB1 antibody, Protein kinase AMP activated non catalytic subunit beta 1 antibody, protein kinase, AMP-activated, beta 1 non-catalytic subunit antibody, protein kinase, AMP-activated, noncatalytic, beta-1 antibody

UniProt: Q9Y478

Pathways: AMPK Signaling, L'effet Warburg