PRKAG3 anticorps (AA 1-210)
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- Antigène Voir toutes PRKAG3 Anticorps
- PRKAG3 (Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3))
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Épitope
- AA 1-210
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PRKAG3 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Réactivité croisée
- Humain
- Purification
- Antigen Affinity Purified
- Immunogène
- Recombinant Human 5\\\'-AMP-activated protein kinase subunit gamma-3 protein (1-210AA)
- Isotype
- IgG
- Top Product
- Discover our top product PRKAG3 Anticorps primaire
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- Indications d'application
- Recommended dilution: WB:1:500-1:2000,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- PRKAG3 (Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3))
- Autre désignation
- PRKAG3 (PRKAG3 Produits)
- Synonymes
- anticorps Ampkg3, anticorps prkag3-a, anticorps PRKAG3, anticorps AMPKG3, anticorps AMPKg3L, anticorps AMPKg3S, anticorps Amkg3, anticorps protein kinase AMP-activated non-catalytic subunit gamma 3, anticorps protein kinase, AMP-activated, gamma 3 non-catalytic subunit S homeolog, anticorps protein kinase, AMP-activated, gamma 3 non-catatlytic subunit b, anticorps protein kinase, AMP-activated, gamma 3 non-catatlytic subunit, anticorps Prkag3, anticorps PRKAG3, anticorps prkag3.S, anticorps prkag3-b
- Sujet
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Background: AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton, probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive.
Aliases: 5 AMP activated protein kinase subunit gamma 3 antibody, 5''-AMP-activated protein kinase subunit gamma-3 antibody, AAKG3_HUMAN antibody, AMPK gamma 3 chain antibody, AMPK gamma3 antibody, AMPK subunit gamma-3 antibody, AMPKG3 antibody, PRKAG3 antibody, Protein kinase AMP activated gamma 3 non catalytic subunit antibody
- UniProt
- Q9UGI9
- Pathways
- AMPK Signaling, Cellular Glucan Metabolic Process, L'effet Warburg
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