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FZD7 anticorps (AA 501-574) (Cy5.5)

FZD7 Reactivité: Humain, Souris, Rat WB, FACS, IF (cc), IF (p) Hôte: Lapin Polyclonal Cy5.5
N° du produit ABIN710056
  • Antigène Voir toutes FZD7 Anticorps
    FZD7 (Frizzled Family Receptor 7 (FZD7))
    Épitope
    • 15
    • 11
    • 9
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 501-574
    Reactivité
    • 59
    • 48
    • 23
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 63
    • 6
    • 5
    • 3
    Lapin
    Clonalité
    • 66
    • 10
    Polyclonal
    Conjugué
    • 37
    • 8
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FZD7 est conjugé à/à la Cy5.5
    Application
    • 64
    • 38
    • 17
    • 12
    • 12
    • 10
    • 10
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain, Souris, Rat
    Homologie
    Dog,Cow,Pig,Chicken,Guinea Pig
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Frizzled 7
    Isotype
    IgG
    Top Product
    Discover our top product FZD7 Anticorps primaire
  • Indications d'application
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    FZD7 (Frizzled Family Receptor 7 (FZD7))
    Autre désignation
    Frizzled 7 (FZD7 Produits)
    Synonymes
    anticorps FzE3, anticorps Fz-7, anticorps Xfz7, anticorps frizzled-7, anticorps frizzled7, anticorps frz-7, anticorps frz7, anticorps fz7, anticorps fzd7-a, anticorps fzd7-b, anticorps fze3, anticorps Fz7, anticorps cFz-7, anticorps fb38g02, anticorps fc44b09, anticorps fz13, anticorps fz7a, anticorps fz7b, anticorps wu:fb38g02, anticorps wu:fc44b09, anticorps zg13, anticorps frizzled class receptor 7, anticorps frizzled class receptor 7 L homeolog, anticorps frizzled class receptor 7b, anticorps FZD7, anticorps fzd7.L, anticorps fzd7, anticorps Fzd7, anticorps fzd7b
    Sujet

    Synonyms: FzE3, Frizzled-7, Fz-7, hFz7, FZD7

    Background: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.

    ID gène
    8324
    UniProt
    O75084
    Pathways
    Signalisation WNT, Stem Cell Maintenance
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