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MST1R anticorps (pTyr1238)

MST1R Reactivité: Humain, Souris, Rat, Singe WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN710336
  • Antigène Voir toutes MST1R Anticorps
    MST1R (Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R))
    Épitope
    • 40
    • 21
    • 14
    • 12
    • 11
    • 11
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr1238
    Reactivité
    • 98
    • 61
    • 40
    • 5
    • 2
    • 1
    • 1
    Humain, Souris, Rat, Singe
    Hôte
    • 109
    • 3
    • 2
    Lapin
    Clonalité
    • 103
    • 11
    Polyclonal
    Conjugué
    • 38
    • 8
    • 7
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp MST1R est non-conjugé
    Application
    • 81
    • 35
    • 23
    • 21
    • 17
    • 15
    • 15
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
     Réactivité croisée
    Humain, Singe, Souris, Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic phosphopeptide derived from human MST1R around the phosphorylation site of Tyr1238
    Isotype
    IgG
    Top Product
    Discover our top product MST1R Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    MST1R (Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R))
    Autre désignation
    Ron (MST1R Produits)
    Synonymes
    anticorps CD136, anticorps CDw136, anticorps PTK8, anticorps RON, anticorps Fv-2, anticorps Fv2, anticorps Ron, anticorps STK, anticorps Cdw136, anticorps Ptk8, anticorps Stk, anticorps macrophage stimulating 1 receptor, anticorps macrophage stimulating 1 receptor (c-met-related tyrosine kinase), anticorps MST1R, anticorps Mst1r
    Sujet

    Synonyms: RON, PTK8, CD136, CDw136, Macrophage-stimulating protein receptor, MSP receptor, Protein-tyrosine kinase 8, p185-Ron, MST1R

    Background: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to MST1 ligand. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces autophosphorylation of RON on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1 or the adapter GAB1. Recruitment of these downstream effectors by RON leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. RON signaling activates the wound healing response by promoting epithelial cell migration, proliferation as well as survival at the wound site. Plays also a role in the innate immune response by regulating the migration and phagocytic activity of macrophages. Alternatively, RON can also promote signals such as cell migration and proliferation in response to growth factors other than MST1 ligand.

    ID gène
    4486
    UniProt
    Q04912
    Pathways
    Signalisation RTK
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